Publications

                                              
Rodgers J, Hughes S, Lindner M, Allen AE, Ebrahimi AS, Storchi R, Peirson SN, Lucas RJ, Hankins MW (2023)
Functional integrity of visual coding following advanced photoreceptor degeneration.
Current biology : CB 33(3): 474-486.e5. Pubmed
Lindner M, Gilhooley MJ, Hughes S, Hankins MW (2022)
Optogenetics for visual restoration: From proof of principle to translational challenges.
Progress in retinal and eye research 91(): 101089. Pubmed
Gilhooley MJ, Lindner M, Palumaa T, Hughes S, Peirson SN, Hankins MW (2022)
A systematic comparison of optogenetic approaches to visual restoration.
Molecular therapy. Methods & clinical development 25(): 111-123. Pubmed
Lindner M (2022)
The thin line between seeing risks and venturing scientific progress.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 260(8): 2773-2774. Pubmed
Künzel SH, Lindner M, Sassen J, Möller PT, Goerdt L, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M, Pfau M (2021)
Association of Reading Performance in Geographic Atrophy Secondary to Age-Related Macular Degeneration With Visual Function and Structural Biomarkers.
JAMA ophthalmology 139(11): 1191-1199. Pubmed
Behning C, Fleckenstein M, Pfau M, Adrion C, Goerdt L, Lindner M, Schmitz-Valckenberg S, Holz FG, Schmid M (2021)
Modeling of atrophy size trajectories: variable transformation, prediction and age-of-onset estimation.
BMC medical research methodology 21(1): 170. Pubmed
Kinder L, Palumaa T, Lindner M (2022)
[Intrinsically photosensitive retinal ganglion cells].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 119(4): 358-366. Pubmed
Birtel TH, Birtel J, Hess K, Clemens AC, Lindner M, Herrmann P, Holz FG, Gliem M (2021)
Analysis of imaging biomarkers and retinal nerve fiber layer thickness in RPGR-associated retinitis pigmentosa.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 259(12): 3597-3604. Pubmed
Gilhooley MJ, Hickey DG, Lindner M, Palumaa T, Hughes S, Peirson SN, MacLaren RE, Hankins MW (2021)
ON-bipolar cell gene expression during retinal degeneration: Implications for optogenetic visual restoration.
Experimental eye research 207(): 108553. Pubmed
Lindner M, Gilhooley MJ, Peirson SN, Hughes S, Hankins MW (2021)
The functional characteristics of optogenetic gene therapy for vision restoration.
Cellular and molecular life sciences : CMLS 78(4): 1597-1613. Pubmed
Lindner M, Gilhooley MJ, Palumaa T, Morton AJ, Hughes S, Hankins MW (2020)
Expression and Localization of Kcne2 in the Vertebrate Retina.
Investigative ophthalmology & visual science 61(3): 33. Pubmed
Müller PL, Pfau M, Treis T, Pascual-Camps I, Birtel J, Lindner M, Herrmann P, Holz FG (2020)
PROGRESSION OF ABCA4-RELATED RETINOPATHY: Prognostic value of demographic, functional, genetic, and imaging parameters.
Retina (Philadelphia, Pa.) 40(12): 2343-2356. Pubmed
Pfau M, von der Emde L, Dysli C, Möller PT, Thiele S, Lindner M, Schmid M, Rubin DL, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2020)
Determinants of Cone and Rod Functions in Geographic Atrophy: AI-Based Structure-Function Correlation.
American journal of ophthalmology 217(): 162-173. Pubmed
Pfau M, Möller PT, Künzel SH, von der Emde L, Lindner M, Thiele S, Dysli C, Nadal J, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2020)
Type 1 Choroidal Neovascularization Is Associated with Reduced Localized Progression of Atrophy in Age-Related Macular Degeneration.
Ophthalmology. Retina 4(3): 238-248. Pubmed
Pfau M, von der Emde L, Dysli C, Thiele S, Möller PT, Lindner M, Nadal J, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2019)
Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration.
Investigative ophthalmology & visual science 60(12): 3992-4001. Pubmed
Bax NM, Valkenburg D, Lambertus S, Klevering BJ, Boon CJF, Holz FG, Cremers FPM, Fleckenstein M, Hoyng CB, Lindner M, (2019)
Foveal Sparing in Central Retinal Dystrophies.
Investigative ophthalmology & visual science 60(10): 3456-3467. Pubmed
von der Emde L, Pfau M, Dysli C, Thiele S, Möller PT, Lindner M, Schmid M, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2019)
Artificial intelligence for morphology-based function prediction in neovascular age-related macular degeneration.
Scientific reports 9(1): 11132. Pubmed
Lindner M, Pfau M, Czauderna J, Goerdt L, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2019)
Determinants of Reading Performance in Eyes with Foveal-Sparing Geographic Atrophy.
Ophthalmology. Retina 3(3): 201-210. Pubmed
Pfau M, Müller PL, von der Emde L, Lindner M, Möller PT, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2020)
MESOPIC AND DARK-ADAPTED TWO-COLOR FUNDUS-CONTROLLED PERIMETRY IN GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION.
Retina (Philadelphia, Pa.) 40(1): 169-180. Pubmed
Birtel J, Lindner M, Mishra DK, Müller PL, Hendig D, Herrmann P, Holz FG, Fleckenstein M, Gliem M, Charbel Issa P (2019)
Retinal imaging including optical coherence tomography angiography for detecting active choroidal neovascularization in pseudoxanthoma elasticum.
Clinical & experimental ophthalmology 47(2): 240-249. Pubmed
Müller PL, Pfau M, Möller PT, Nadal J, Schmid M, Lindner M, de Sisternes L, Stöhr H, Weber BHF, Neuhaus C, Herrmann P, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2018)
Choroidal Flow Signal in Late-Onset Stargardt Disease and Age-Related Macular Degeneration: An OCT-Angiography Study.
Investigative ophthalmology & visual science 59(4): AMD122-AMD131. Pubmed
Pfau M, Lindner M, Gliem M, Steinberg JS, Thiele S, Finger RP, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2018)
Mesopic and dark-adapted two-color fundus-controlled perimetry in patients with cuticular, reticular, and soft drusen.
Eye (London, England) 32(12): 1819-1830. Pubmed
Pfau M, Lindner M, Goerdt L, Thiele S, Nadal J, Schmid M, Schmitz-Valckenberg S, Sadda SR, Holz FG, Fleckenstein M, (2019)
PROGNOSTIC VALUE OF SHAPE-DESCRIPTIVE FACTORS FOR THE PROGRESSION OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION.
Retina (Philadelphia, Pa.) 39(8): 1527-1540. Pubmed
Lindner M, Kosanetzky S, Pfau M, Nadal J, Gördt LA, Schmitz-Valckenberg S, Schmid M, Holz FG, Fleckenstein M, (2018)
Local Progression Kinetics of Geographic Atrophy in Age-Related Macular Degeneration Are Associated With Atrophy Border Morphology.
Investigative ophthalmology & visual science 59(4): AMD12-AMD18. Pubmed
Pfau M, Lindner M, Steinberg JS, Thiele S, Brinkmann CK, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2018)
Visual field indices and patterns of visual field deficits in mesopic and dark-adapted two-colour fundus-controlled perimetry in macular diseases.
The British journal of ophthalmology 102(8): 1054-1059. Pubmed
Pfau M, Lindner M, Müller PL, Birtel J, Finger RP, Harmening WM, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2017)
Effective Dynamic Range and Retest Reliability of Dark-Adapted Two-Color Fundus-Controlled Perimetry in Patients With Macular Diseases.
Investigative ophthalmology & visual science 58(6): BIO158-BIO167. Pubmed
Oishi M, Oishi A, Lindner M, Pfau M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2017)
Structural Changes in Optical Coherence Tomography Underlying Spots of Increased Autofluorescence in the Perilesional Zone of Geographic Atrophy.
Investigative ophthalmology & visual science 58(7): 3303-3310. Pubmed
Pfau M, Goerdt L, Schmitz-Valckenberg S, Mauschitz MM, Mishra DK, Holz FG, Lindner M, Fleckenstein M (2017)
Green-Light Autofluorescence Versus Combined Blue-Light Autofluorescence and Near-Infrared Reflectance Imaging in Geographic Atrophy Secondary to Age-Related Macular Degeneration.
Investigative ophthalmology & visual science 58(6): BIO121-BIO130. Pubmed
Lindner M, Nadal J, Mauschitz MM, Lüning A, Czauderna J, Pfau M, Schmitz-Valckenberg S, Holz FG, Schmid M, Fleckenstein M (2017)
Combined Fundus Autofluorescence and Near Infrared Reflectance as Prognostic Biomarkers for Visual Acuity in Foveal-Sparing Geographic Atrophy.
Investigative ophthalmology & visual science 58(6): BIO61-BIO67. Pubmed
Lindner M, Lambertus S, Mauschitz MM, Bax NM, Kersten E, Lüning A, Nadal J, Schmitz-Valckenberg S, Schmid M, Holz FG, Hoyng CB, Fleckenstein M, (2017)
Differential Disease Progression in Atrophic Age-Related Macular Degeneration and Late-Onset Stargardt Disease.
Investigative ophthalmology & visual science 58(2): 1001-1007. Pubmed
Holz FG, Sadda SR, Staurenghi G, Lindner M, Bird AC, Blodi BA, Bottoni F, Chakravarthy U, Chew EY, Csaky K, Curcio CA, Danis R, Fleckenstein M, Freund KB, Grunwald J, Guymer R, Hoyng CB, Jaffe GJ, Liakopoulos S, Monés JM, Oishi A, Pauleikhoff D, Rosenfeld PJ, Sarraf D, Spaide RF, Tadayoni R, Tufail A, Wolf S, Schmitz-Valckenberg S, (2017)
Imaging Protocols in Clinical Studies in Advanced Age-Related Macular Degeneration: Recommendations from Classification of Atrophy Consensus Meetings.
Ophthalmology 124(4): 464-478. Pubmed
Pfau M, Lindner M, Fleckenstein M, Finger RP, Rubin GS, Harmening WM, Morales MU, Holz FG, Schmitz-Valckenberg S (2017)
Test-Retest Reliability of Scotopic and Mesopic Fundus-Controlled Perimetry Using a Modified MAIA (Macular Integrity Assessment) in Normal Eyes.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 237(1): 42-54. Pubmed
Lindner M, Fang PP, Steinberg JS, Domdei N, Pfau M, Krohne TU, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2016)
OCT Angiography-Based Detection and Quantification of the Neovascular Network in Exudative AMD.
Investigative ophthalmology & visual science 57(14): 6342-6348. Pubmed
Lambertus S, Lindner M, Bax NM, Mauschitz MM, Nadal J, Schmid M, Schmitz-Valckenberg S, den Hollander AI, Weber BH, Holz FG, van der Wilt GJ, Fleckenstein M, Hoyng CB, (2016)
Progression of Late-Onset Stargardt Disease.
Investigative ophthalmology & visual science 57(13): 5186-5191. Pubmed
Leitner MG, Michel N, Behrendt M, Dierich M, Dembla S, Wilke BU, Konrad M, Lindner M, Oberwinkler J, Oliver D (2016)
Direct modulation of TRPM4 and TRPM3 channels by the phospholipase C inhibitor U73122.
British journal of pharmacology 173(16): 2555-69. Pubmed
Fleckenstein M, Grassmann F, Lindner M, Pfau M, Czauderna J, Strunz T, von Strachwitz C, Schmitz-Valckenberg S, Holz FG, Weber BH (2016)
Distinct Genetic Risk Profile of the Rapidly Progressing Diffuse-Trickling Subtype of Geographic Atrophy in Age-Related Macular Degeneration (AMD).
Investigative ophthalmology & visual science 57(6): 2463-71. Pubmed
Schmitz-Valckenberg S, Nadal J, Fimmers R, Lindner M, Holz FG, Schmid M, Fleckenstein M, (2016)
Modeling Visual Acuity in Geographic Atrophy Secondary to Age-Related Macular Degeneration.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 235(4): 215-24. Pubmed
Fang PP, Lindner M, Steinberg JS, Müller PL, Gliem M, Charbel Issa P, Krohne TU, Holz FG (2016)
[Clinical applications of OCT angiography].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 113(1): 14-22. Pubmed
Fang PP, Harmening WM, Müller PL, Lindner M, Krohne TU, Holz FG (2016)
[Technical principles of OCT angiography].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 113(1): 6-13. Pubmed
Lindner M, Böker A, Mauschitz MM, Göbel AP, Fimmers R, Brinkmann CK, Schmitz-Valckenberg S, Schmid M, Holz FG, Fleckenstein M, (2015)
Directional Kinetics of Geographic Atrophy Progression in Age-Related Macular Degeneration with Foveal Sparing.
Ophthalmology 122(7): 1356-65. Pubmed
Lindner M, Bezatis A, Czauderna J, Becker E, Brinkmann CK, Schmitz-Valckenberg S, Fimmers R, Holz FG, Fleckenstein M (2015)
Choroidal thickness in geographic atrophy secondary to age-related macular degeneration.
Investigative ophthalmology & visual science 56(2): 875-82. Pubmed
Wilke BU, Lindner M, Greifenberg L, Albus A, Kronimus Y, Bünemann M, Leitner MG, Oliver D (2014)
Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors.
Nature communications 5(): 5540. Pubmed
Grassmann F, Schoenberger PG, Brandl C, Schick T, Hasler D, Meister G, Fleckenstein M, Lindner M, Helbig H, Fauser S, Weber BH (2014)
A circulating microrna profile is associated with late-stage neovascular age-related macular degeneration.
PloS one 9(9): e107461. Pubmed
Fleckenstein M, Schmitz-Valckenberg S, Lindner M, Bezatis A, Becker E, Fimmers R, Holz FG, (2014)
The "diffuse-trickling" fundus autofluorescence phenotype in geographic atrophy.
Investigative ophthalmology & visual science 55(5): 2911-20. Pubmed
Lindner M, Bertelmann T (2014)
On the ocular findings in ochronosis: a systematic review of literature.
BMC ophthalmology 14(): 12. Pubmed
Lindner M, Leitner MG, Halaszovich CR, Hammond GR, Oliver D (2011)
Probing the regulation of TASK potassium channels by PI4,5P₂ with switchable phosphoinositide phosphatases.
The Journal of physiology 589(Pt 13): 3149-62. Pubmed